本文作者应用~3 H标记的二羟基外搏停(~3H-DHA,一种β受体阻滞剂),与大鼠肺组织膜进行结合,直接证明了肺内存在β_1和β_2两型肾上腺素能受体,其比例为1:3。~3H-DHA与肺组织膜的结合具有高度亲和力和立体结构特异性,其药理学性质表明是结合在β受体上。此种特异性结合可代表总结合力的90％。在此基础上,作者应用了某些β受体阻滞剂来置换~3H-DHA的结合,其中有些是属于非选择性β阻滞剂,即对β_1和β_2受体都有同样的亲和力,有的则是β_1受体选择性阻滞剂。结果表明,非选择性β阻滞剂如噻吗心安 The authors used ~ 3H labeled dihydroxy-pacing (~ 3H-DHA, a beta-blocker), and lung tissue in rats with a combination of direct evidence of pulmonary β1 and β2 exist two types of adrenal The prime receptor, the ratio of 1: 3. ~ 3H-DHA and lung tissue membrane binding with high affinity and stereospecificity, the pharmacological properties that are bound to the β receptor. Such specific binding can represent 90% of the total binding force. Based on this, the authors used some beta-blockers to displace the binding of ~ 3H-DHA, some of which are non-selective beta-blockers that have the same affinity for beta 1 and beta 2 receptors, Some are beta 1 receptor selective blockers. The results show that non-selective beta blockers such as timolol