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本文收集6例克山病,1例扩张型心肌病和5例意外事故死亡病例(作对照)尸检材料,分别取左,右心室肌和横膈肌,作肌细胞的细胞色素氧化酶活性产物的电镜观察,对各组病例肌细胞酶活性变化进行对比分析。结果表明,对照组心肌细胞色素氧化酶活性变化不明显;克山病组横膈肌细胞色素氧化酶活性产物轻度脱失,心肌细胞色素氧化酶活性产物脱失明显。而扩张性心肌病心肌细胞色素氧化酶活性虽有降低,但不如克山病明显。并对各组病例肌细胞色素氧化酶活性变化的意义作简要的讨论。
In this paper, 6 cases of Keshan disease, 1 case of dilated cardiomyopathy and 5 cases of accidental death (control) autopsy material were collected from the left and right ventricular and diaphragmatic muscle cells were made for the activity of cytochrome oxidase Electron microscopy, the changes of muscle cell enzyme activity in each group were compared. The results showed that the changes of myocardial cytochrome oxidase activity in the control group were not obvious. The products of diaphragmatic muscle cytochrome oxidase activity in Keshan disease group were slightly lost and the products of myocardial cytochrome oxidase activity were lost significantly. The dilated cardiomyopathy myocardial cytochrome oxidase activity although reduced, but not as Keshan disease significantly. The significance of changes of myocyte cytochrome oxidase activity in each group was briefly discussed.