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探讨辣椒素药膜对增生性瘢痕的防治作用。方法:对烧伤后半年以上伴有瘙痒症状的增生性瘢痕局部外用药膜,每天坚持使用 10 h以上。用药后随时观察瘙痒症状,并在第 15 d和 3个月后观察瘢痕硬度、血流量及瘢痕的颜色。结果:药膜使用早期即显示其明确的镇痛止痒作用;使用3个月后其有明显降低瘢痕硬度、减少血流量和改善瘢痕颜色的功效。结论:辣椒素药膜对增生性瘢痕具有明确防治作用,改善瘙痒症状尤其明显,具有广泛的应用前景。
To investigate the preventive and therapeutic effects of capsaicinoid film on hypertrophic scars. Methods: The local topical film of hypertrophic scars with pruritus for more than half a year after burn was used more than 10 hours per day. The symptoms of pruritus were observed at any time after treatment, and the scar hardness, blood flow, and scar color were observed after 15 and 3 months. Results: The early use of the drug film showed its clear analgesic and antipruritic effects; after 3 months of use, it significantly reduced the hardness of the scar, reduced blood flow, and improved the color of the scar. Conclusion: The capsaicinoid film has a definite preventive and therapeutic effect on hypertrophic scars. It is particularly evident that it improves the symptoms of pruritus and has a wide application prospect.