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目的：对小细胞恶性肿瘤进行科学的病理学分类。方法：对２２例小细胞恶性肿瘤行临床、病理形态和多种免疫组化与电镜观察分析。结果：将２２个病例分为４组：（１）Ｅｗｉｎｇ瘤和神经内分泌肿瘤组９例（骨内Ｅｗｉｎｇ瘤３冽、骨外者１例，Ａｓｋｉｎ瘤１例，原始神经外胚层肿瘤１例，节细胞性神经母细胞瘤１例和神经内分泌癌２例）；（２）胚胎性横纹肌肉瘤８例；（３）结外恶性淋巴瘤３例；（４）腹腔内硬化性小圆细胞瘤和小细胞恶性间皮瘤各１例。结论：小细胞肿瘤的种类繁多，对其诊断应密切结合临床，同时辅以多种特殊检查。
Objective: To make a scientific pathological classification of small cell malignant tumors. Methods: Twenty-two cases of small-cell malignant tumors were examined by clinical and pathological features, and analyzed by immunohistochemistry and electron microscopy. RESULTS: Twenty-two cases were divided into 4 groups: (1) Ewing tumor and neuroendocrine tumor group (9 cases) (3 cases of intraepithelial Ewing tumor, 1 case of extraosseous, 1 case of Askin tumor, 1 case of primitive neuroectodermal tumor, There were 1 case of ganglion cell neuroblastoma and 2 cases of neuroendocrine carcinoma); (2) 8 cases of embryonal rhabdomyosarcoma; (3) 3 cases of extranodal malignant lymphoma; (4) Intraperitoneal sclerosing myeloma and One case of small cell malignant mesothelioma. Conclusion: There are many types of small cell tumors. The diagnosis should be closely combined with the clinical, supplemented by a variety of special examinations.