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作者对644例Ⅰ、Ⅱ期(T_1N_0M_0,T_1N_1Mo)乳癌作了平均18.2年的随访,重点观察早期乳癌经乳房切除后可否长期生存,肿瘤大小和淋巴结状态对生存的影响及乳房切除后用或不用辅助治疗能否治愈。结果:23％死于复发,3％有复发病变(存活),74％无复发。复发与最初病变的大小有关。复发中的16％和死亡的25％均发生于第二个10年随访中。在第二个10年查见复发的比例与初诊时原发肿瘤的期别呈负相关。如按肿瘤大小作成层(Stratifed)分析,T_1N_0M_0肿瘤直径≤1cm者20年无复发,明显好于 T_1N_0M_0肿瘤直径1.1～2cm者(86％比69％)。如
The authors had an average of 18.2 years follow-up of 644 stage I and II (T_1N_0M_0, T_1N_1Mo) breast cancers, focusing on the long-term survival of early breast cancer after mastectomy, the impact of tumor size and lymph node status on survival, and the use of or without mastectomy. Can adjuvant treatment be cured? Results: 23% died of recurrence, 3% had recurrent disease (survival), and 74% had no recurrence. Recurrence is related to the size of the initial lesion. 16% of relapses and 25% of deaths occurred during the second 10-year follow-up. The proportion of recurrences seen in the second 10 years was negatively correlated with the stage of primary tumors at the time of initial diagnosis. According to the tumor size (stratifed) analysis, T_1N_0M_0 tumor diameter ≤ 1cm no recurrence 20 years, significantly better than T_1N_0M_0 tumor diameter of 1.1 ~ 2cm (86% to 69%). Such as