感染是新生儿发病和死亡的主要原因。研究证明,新生儿,尤其是早产新生儿对感染的易感性高于成人,并常发展成较重的病变。新生儿宿主防御机制低下由多种因素引起,如 T 细胞、B 细胞和粒细胞的低反应性,粒细胞和干细胞的数量减少。虽然这些缺陷都分别 Infection is the leading cause of morbidity and mortality in newborns. Studies have shown that newborns, especially premature neonates, are more susceptible to infection than adults and often develop severe pathologies. Low neonatal host defense mechanisms are caused by a variety of factors, such as hyporesponsiveness of T cells, B cells, and granulocytes, with reduced numbers of granulocytes and stem cells. Although these defects are different