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小鼠ｉｐＰＳＰ１００ｍｇ／ｋｇ，连续７ｄ，可明显增加脾重；能显著促进腹腔Ｍ，吞噬功能，单核Ｍ系统清除血液碳粒的速率及血清溶血索的形成；并能显著对抗Ｃｙ所致小鼠胸腺与脾脏萎缩、腹腔Ｍ吞噬功能降低、血清溶血素形成减少及脾抗体形成细胞功能的抑制作用。ＰＳＰ还可显著促进ＣｏｎＡ诱导的体外小鼠淋巴细胞转化，最适剂量为１０μｇ／ｍｌ～１６０μｇ／ｍｌ。另外，ｉｐＰＳＰ１００ｍｇ／ｋｇ，连续１２ｄ，可明显促进小鼠Ｋ细胞ＡＤＣＣ活性。结果提示ＰＳＰ对小鼠免疫功能有广泛的调节作用。
Mice ipPSP100mg / kg, for 7 days, can significantly increase the spleen weight; can significantly promote the peritoneal M, phagocytic function, mononuclear M system to clear blood carbon particles and the formation of serum hemolysin; and can significantly antagonize Cy-induced mice Thymus and spleen atrophy, lower peritoneal M phagocytic function, reduced formation of serum hemolysin and spleen antibody-forming cell function inhibition. PSP can also significantly promote ConA-induced mouse lymphocyte transformation in vitro, the optimal dose of 10μg / ml ~ 160μg / ml. In addition, ipPSP100mg / kg, continuous 12d, can significantly promote mouse K cells ADCC activity. The results suggest that PSP has a broad regulatory role in immune function in mice.