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用表面张力-浓度曲线法系统地研究了环糊精(CD)和羧甲基糖淀粉钠(Na-CMA)与H(CF_2)_(12)CO_2K(1),Cl(CF_2)_nCH_2CH_2N~+(CH_3)_3I~-[n=8(3),10(5)]和相应的碳氢表面活性剂(24和6)的相互作用。由于几何尺寸的限制,碳氟表面活性剂不能与α-CD形成包结络合物,但3与β-CD形成的包结络合物的稳定性远大于相应的碳氢受物4、3与β-CD的相互作用是熵驱动过程,而C_(12)H_(25)N~+(CH_3)_3I~-(6)则是焓有利的。与具有“预组织化”内穴的CD不同,糖淀粉的包结是与大分子从线团到螺旋构象变化的协同过程,由于缺乏宿主-受物间的亲脂相互作用,Na-CMA不能与所有的碳氟受物形成包结络合物。
The effects of cyclodextrin (CD) and Na-CMA and H (CF_2) _ (12) CO_2K (1), Cl (CF_2) _nCH_2CH_2N ~ + (CH_3) _3I ~ - [n = 8 (3), 10 (5)] and the corresponding hydrocarbon surfactants (24 and 6). Due to geometrical constraints, fluorocarbon surfactants can not form inclusion complexes with α-CD, but the stability of inclusion complexes formed with β-CD is much greater than that of the corresponding hydrocarbon acceptors 4,3 The interaction with β-CD is the entropy-driven process, while the enthalpy of C_ (12) H_ (25) N ~ + (CH_3) _3I ~ - (6) Unlike CDs with “pre-organized” pockets, inclusion of glycated starch is a synergistic process with changes in macromolecules from coil to helical conformation. Na-CMA does not function due to lack of host-receptor lipophilic interactions Encapsulation complexes with all fluorocarbon receptors.