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气道高反应性(airway hyperresponsiveness,AHR)和慢性炎症是哮喘的两个重要病理特征。此外,人们逐渐认识到哮喘的另一个重要病理特征,即存在于慢性炎症之后气道结构的改变—气道重塑。客观的激发试验,如乙酰甲胆碱支气管激发试验被看作哮喘诊断的金标准。呼出气一氧化氮水平(FeNO)是气道炎症的标志物,近几年成为儿童支气管哮喘诊断的有力依据。ΔFVC(PC20引起FVC下降的百分率)在评估哮喘治疗方面可能比
Airway hyperresponsiveness (AHR) and chronic inflammation are two important pathological features of asthma. In addition, people are gradually recognizing another important pathological feature of asthma, that is, the change of airway structure after chronic inflammation - airway remodeling. Objective provocation tests, such as the methacholine bronchial provocation test, are considered the gold standard for the diagnosis of asthma. Exhaled air nitric oxide levels (FeNO) is a marker of airway inflammation in recent years has become a strong basis for the diagnosis of bronchial asthma in children. ΔFVC (the percentage of PC20 that causes a decrease in FVC) may be more valuable in assessing asthma treatment