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观察端粒酶活性在胃癌及胃癌前病变细胞和组织中的表达．方法：采用蜡膜介导热启动端粒重复扩增PCR模型方法．结果：胃癌细胞株端粒酶活性3株均呈阳性，在38例胃癌中，32例端粒酶活性阳性，其中进展期胃癌为30／35，早期胃癌为2／3，而邻近胃组织为2／38，在29例胃癌前病变中，5例端粒酶活性阳性，其中不典型增生轻度、中度及重度分别为1／8，l／4和1／3，肠上度化生和胃息肉分别为1／8和1／6．结论：端粒酶的活化在胃癌的发生、形成及发展过程中可能起着非常重要的作用．
Observe the expression of telomerase activity in gastric cancer and precancerous lesion cells and tissues. 3. Methods: The telomere repeat amplification PCR model method was initiated by the introduction of wax film. Results: The telomerase activity in gastric cancer cell lines was positive in all 3 strains. In 38 cases of gastric cancer, 32 cases had positive telomerase activity, among which advanced gastric cancer was 30/35, early gastric cancer was 2/3, and adjacent gastric tissue was Of the 29 cases of gastric precancerous lesions, 2/38, 5 cases had positive telomerase activity, among which mild, moderate, and severe dysplasia were 1/8, 1/4, and 1/3, respectively. Intestinal metaplasia Gastric polyps are 1/8 and 1/6, respectively. Conclusion: Telomerase activation may play an important role in the occurrence, formation and development of gastric cancer.