Castleman 病是一种较少见的淋巴组织病,可以发生沿淋巴链走行的任何部位,纵隔最常见。组织学表现分两型:一种为透明血管型,占90％;另一种为浆细胞型。作者回顾性分析了10例纵隔Castleman病病人的临床资料、影像物点及病理结果。男性3例,女性7例,年龄18～25岁,平均23岁。9例病人经纵隔肿块活检确诊,1例经颈部淋巴结切除活检证实。10 Castleman’s disease is a rare form of lymphoid disease that can occur anywhere along the lymphatic chain, the mediaiest being the most common. Histological manifestations divided into two types: one is transparent vascular type, accounting for 90%; the other is plasma cell type. The authors retrospectively analyzed the clinical data, imaging findings and pathological findings of 10 patients with mediastinal Castleman’s disease. 3 males and 7 females, aged from 18 to 25 years with an average of 23 years old. Nine patients were diagnosed by mediastinal mass biopsy, and one was confirmed by cervical lymph node dissection biopsy. 10