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没食子酸乙酯(Ethyl Gallate)系我们在寻找盐肤木有效成分时发现的一种单体,白色结晶,熔点143～145℃,化学结构式为:现已人工合成。它在心血管方面具有较好的活性。今将1975年起所进行的药理工作总结如下。方法和结果一、静脉注射没食子酸乙酯对麻醉犬器官血流量和血管阻力的影响犬6只,13.5～22公斤,戊巴比妥钠静脉麻醉,用水银检压计测右颈动脉血压,插入气管套管行人工呼吸,沿左侧第四肋间开胸,以MF—46型电磁流量计不同直径的卡式探头置于左冠状动脉旋支、颈内动脉、股动脉的周围,测定其血流量并计算血管阻力。
Ethyl Gallate (Ethyl Gallate) is a monomer found in the search for active ingredients of Rhus chinensis. It is a white crystal with a melting point of 143 to 145°C. Its chemical structural formula is: It has been synthesized artificially. It has a good cardiovascular activity. The pharmacological work conducted since 1975 is summarized below. Methods and Results I. Effects of intravenous injection of ethyl gallate on the blood flow and vascular resistance of anesthetized dogs: 6 dogs, 13.5-22 kg, intravenous anesthesia of pentobarbital sodium, and blood pressure measurement of the right carotid artery using mercury pressure Insert the tracheal tube into the artificial respiration and open the chest along the left fourth intercostal space. Use the CM-46 electromagnetic flowmeter with different diameters of the cassette probe to be placed around the left coronary artery, internal carotid artery, and femoral artery. Its blood flow and calculate vascular resistance.