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目的应用BODE评分评价清热肃肺化痰方治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效。方法将符合诊断标准的AECOPD患者53例分为两组:中药组35例和常规组18例,常规组规范化治疗方案,中药组在其基础上加清热肃肺化痰方,疗程为8周。对治疗前后对患者AECOPD缓解时间、住院持续时间和BODE评分评价。结果中药组AECOPD住院时间和BODE评分明显优于常规组,差异有统计学意义(P<0.05),但两组AECOPD缓解时间差异不大;中药组BODE评分前后对比,差异有统计学意义(P<0.05),而常规组改善不明显。结论清热肃肺化痰法对AECOPD有较好的治疗作用。
Objective To evaluate the clinical efficacy of “Qingre Suihu Huatan Decoction” in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) by BODE score. Methods Fifty-three patients with AECOPD meeting the diagnostic criteria were divided into two groups: 35 cases in the traditional Chinese medicine group and 18 cases in the conventional group. The routine treatment group was given standardized treatment. Patients before and after treatment of AECOPD remission time, hospital duration and BODE score evaluation. Results The length of hospital stay and BODE score of AECOPD in Chinese medicine group were significantly better than those in conventional group (P <0.05), but there was no significant difference in AECOPD remission time between the two groups (P> 0.05) <0.05), while the improvement in the conventional group was not obvious. Conclusion Heat-clearing, sun-clearing and phlegm-resolving therapy has a good therapeutic effect on AECOPD.