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背景:马方综合征心血管病变的主要特征为近端主动脉的进行性扩张。目前尚不清楚此类患者是否会出现左室功能障碍。目的:联合应用磁共振成像(MRI)和组织多普勒成像(TDI)技术,评价无明显心脏瓣膜病的马方综合征患者的左室功能。方法和结果:研究共纳入26例无明显心脏瓣膜病的马方综合征患者(平均年龄32.0±10.9岁,男性12例),同时选取26例年龄和性别均匹配的对象作为对照。
Background: The main characteristic of Marfan syndrome cardiovascular disease is the progressive dilatation of the proximal aorta. It is unclear whether these patients have LV dysfunction. OBJECTIVE: To evaluate left ventricular function in patients with Marfan syndrome without obvious valvular heart disease by using magnetic resonance imaging (MRI) and tissue Doppler imaging (TDI). Methods and Results: A total of 26 patients with Marfan syndrome without significant valvular heart disease (mean age 32.0 ± 10.9 years, 12 males) were enrolled in the study. Twenty-six age- and gender-matched subjects were selected as controls.