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本文对871例门诊及住院孕妇,应用 SP_1放射免疫法测血 SP_1值1074次,其中最多测5次,均用毛细玻璃管取孕妇耳血0.2ml,离心分离血清,-20℃贮存待测。同时测尿比值39例、血 hPL 值58例做为对照观察。结果表明,正常妊娠4周血 SP_1值开始随孕周的增加而增加,至38孕周时达高峰值(179μg/ml),39周后稍有下降,并维持到分娩。本文以各孕周血 SP_1值的第90和第10百分位数做为正常范围的上下限,以此对异常妊娠进行观察。轻、中度妊高征41例,测44次,5例血 SP_1值低于正常同孕周的第10百分位数(12.2%),重度妊高征53例,测73次,其中末次测定血 SP_1值低值者24例(45.3%),妊高征胎盘病理组织学及超微结构临床各型
In this paper, 871 outpatients and hospitalized pregnant women, the application of SP_1 radioimmunoassay SP_1 value of 1074 times, of which up to 5 times, were using capillary glass tube to take pregnant women ear blood 0.2ml, centrifuged serum, -20 ℃ storage to be tested. 39 cases of urine test at the same time, blood hPL value of 58 cases as a control. The results showed that at 4 weeks of normal pregnancy, serum SP_1 began to increase with the increase of gestational age, reached the peak value of 38 weeks (179μg / ml), decreased slightly after 39 weeks and maintained until delivery. In this paper, the 90th and 10th percentile of the SP_1 value of each gestational week were used as the upper and lower limits of the normal range to observe the abnormal pregnancy. 41 cases of mild to moderate pregnancy-induced hypertension, measured 44 times, 5 cases of blood SP_1 value below the tenth week of normal gestational weeks (12.2%), severe PIH in 53 cases, measured 73 times, of which the last Twenty-four patients (45.3%) had low serum SP_1 values. The placenta histopathology and ultrastructural features of pregnancy-induced hypertension