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目的探讨瑞素口服液与黄芪颗粒治疗肺结核合并营养不良的疗效。方法将64例初治肺结核合并营养不良患者随机分为观察组和对照组,每组32例。2组均予以抗痨治疗,对照组在抗痨治疗的基础上予以瑞素口服液治疗,观察组在对照组基础上予以黄芪颗粒治疗。治疗2周后,比较2组治疗前后血生化和免疫指标变化情况。结果治疗后,2组生化指标ALB、Hb和BMI均高于治疗前(P<0.05);2组免疫指标CD_3和CD_4均高于治疗前(P<0.05);观察组CD_3和CD_4高于对照组(P<0.05)。结论营养支持治疗有助于改善肺结核合并营养不良,黄芪颗粒同时可提高免疫功能,优于单纯肠内营养。
Objective To investigate the curative effect of Ruisu Oral Liquid and Huangqi Granules in the treatment of pulmonary tuberculosis complicated with malnutrition. Methods 64 patients with newly diagnosed pulmonary tuberculosis complicated with malnutrition were randomly divided into observation group and control group, 32 cases in each group. The two groups were treated with anti-tuberculosis, while the control group was treated with Ruisu oral solution on the basis of anti-tuberculosis treatment. The observation group was treated with astragalus membranaceus on the basis of the control group. After 2 weeks of treatment, the changes of blood biochemistry and immune index before and after treatment were compared between the two groups. Results After treatment, the biochemical indexes ALB, Hb and BMI of two groups were higher than those before treatment (P <0.05); the immune indexes CD_3 and CD_4 of two groups were higher than those before treatment (P <0.05) Group (P <0.05). Conclusion Nutritional supportive therapy can improve pulmonary tuberculosis with malnutrition. Astragalus membranaceus can improve immune function at the same time, which is better than simple enteral nutrition.