随着分子生物学和遗传学研究的不断进展,遗传性疾病越来越引起人们的关注。遗传性疾病分为单基因遗传、多基因遗传和染色体异常三大种类,多是由基因突变引起,其中基因突变根据其对基因的影响可分为三种,包括同义突变(same sense mutation)、错义突变(missense mutation)和无义突变(nonsense mutation)。无义突变是指因为某个碱基 With the continuous progress of molecular biology and genetics, genetic diseases have drawn more and more attention. Hereditary diseases are divided into three types: single gene, multi-gene and chromosomal abnormalities, mostly caused by gene mutations. According to their influence on genes, gene mutations can be divided into three types, including the same sense mutation, Missense mutation and nonsense mutation. Nonsense mutations are because of a base