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作者为研究急性肺炎患者痰中的菌种结构,对90例患者在入院初期及其后2～3周进行了动态检查。自150份痰样中分离培养出各种细菌174株,其中最常见的是肺炎链球菌(48.85%),其次为化脓链球菌(17.24%)和流感嗜血杆菌(1.36%);分离出单一细菌者占68%,二种细菌混合存在者占32%。测定分离菌数量对确定病原菌十分重要。病原菌不同于并存的其他菌,据认为,其痰中含量10~7形成菌落单位(KOE)/ml 以上者具有病原学意义。此项检查结果表明,74%患者的痰菌量高达10~8和10~9KOE/ml,多为肺炎链球菌,而金黄色葡萄球菌、表皮葡萄球菌和大肠杆菌则为10~7KOE/ml。此外,75例患者的动态观察显示抗体滴度升高,证明分离菌具有致病作用。
In order to study the bacterial species in sputum from patients with acute pneumonia, 90 patients underwent dynamic examinations at the beginning of admission and at 2 to 3 weeks thereafter. A total of 174 strains of bacteria were isolated and cultured from 150 sputum samples. The most common ones were Streptococcus pneumoniae (48.85%), followed by Streptococcus pyogenes (17.24%) and Haemophilus influenzae (1.36%), 68% of bacteria, two bacteria mixed accounted for 32%. Determination of the number of isolates to determine the pathogen is very important. Pathogenic bacteria other than the coexistence of other bacteria, it is believed that the sputum content of 10 to 7 forming colony units (KOE) / ml above has etiological significance. The test results showed that 74% of patients sputum volume as high as 10 ~ 8 and 10 ~ 9KOE / ml, mostly Streptococcus pneumoniae, while Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli was 10 ~ 7KOE / ml. In addition, the dynamic observation of 75 patients showed an increase in antibody titer, demonstrating that the isolate has a pathogenic effect.