多发性骨髓瘤是浆细胞异常增殖所致的一种恶性肿瘤。本病主要侵犯骨与骨髓,其损害骨质所引起的骨痛、骨骼畸形与病理性骨折等表现,具有提示诊断的意义,且为多数医者所熟识,故典型病例多可循此得到确诊。然而,由于本病血液、免疫与代谢的异常,瘤细胞的异位浸润与髓外浆细胞瘤的形成;加之各类症状出现的先后不一,构成患者表 Multiple myeloma is a malignant tumor caused by abnormal proliferation of plasma cells. The disease mainly affects the bone and bone marrow, its damage to bone caused by bone pain, skeletal deformities and pathological fracture performance, with the significance of the diagnosis, and for most doctors are familiar, so many typical cases can be confirmed by this. However, due to abnormal blood, immune and metabolic abnormalities, the ectopic infiltration of tumor cells and the formation of extramedullary plasmacytoma; together with the different types of symptoms, the patient table