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目的:评价氯胺酮-芬太尼亚麻醉剂量辅助小儿区域麻醉的临床疗效。方法:将该院2010年3月—2013年6月间收治的100例行四肢、腹部手术的患儿,随机分为对照组50例和观察组50例;对照组患者予单用氯胺酮常规麻醉,观察组患者予氯胺酮-芬太尼联合麻醉;对两组患者所使用药物的麻醉剂量和唤醒时间、手术时间,以及术后患儿生活质量等进行对比分析。结果:两组患儿的手术时间对比,其差异无统计学意义(P>0.05);观察组患者麻醉剂用量较少,并且术后唤醒时间较短,手术麻醉后生活质量较高;与对照组比较,其差异有统计学意义(P<0.05)。结论:氯胺酮-芬太尼联合使用于小儿区域麻醉中,其临床疗效较好,减少麻醉剂用量,缩短麻醉后唤醒时间,提高患儿术后生活质量。
PURPOSE: To evaluate the clinical efficacy of ketamine-fentanyl anesthesia in assisting pediatric regional anesthesia. Methods: A total of 100 pediatric patients with limbs and abdominal surgery admitted to our hospital from March 2010 to June 2013 were randomly divided into control group (n = 50) and observation group (n = 50). Patients in the control group were given ketamine alone . The patients in the observation group were given ketamine-fentanyl anesthesia. The anesthetic dose, wake-up time, operation time and quality of life of children in the two groups were compared. Results: There was no significant difference between the two groups in the operation time (P> 0.05). The observation group had less anesthetic agent, shorter awakening time and higher quality of life after anesthesia. Compared with the control group The difference was statistically significant (P <0.05). Conclusion: The combination of ketamine and fentanyl for regional anesthesia in children has good clinical curative effect, reduces the dosage of anesthetic, shortens the awakening time after anesthesia and improves postoperative quality of life in children.