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目的:观察创愈膏的抗炎作用。方法:采用二甲苯致小鼠耳廓肿胀、醋酸致小鼠腹腔毛细血管通透性增高及大鼠松节油气囊肉芽肿增生的炎症性模型。结果:创愈膏能显著抑制小鼠耳廓肿胀及醋酸致小鼠腹腔毛细血管通透性增高;创愈膏对大鼠松节油气囊肉芽肿增生有明显的抑制作用。结论:创愈膏可以抑制急性炎症及肉芽肿组织的增生。具有良好的抗炎作用。
Objective: To observe the anti-inflammatory effects of Chuang Yu Gao. METHODS: The mouse ear swelling caused by xylene, acetic acid-induced increased capillary permeability in the abdominal cavity of the mice, and the inflammatory model of rat turpentine balloon granuloma hyperplasia. Results: Chuangyu ointment could significantly inhibit the swelling of mouse ear and the increase of acetic acid-induced permeability of capillary in abdominal cavity of mice. Chuangyu ointment significantly inhibited the proliferation of rat turpentine balloon granuloma. Conclusion: Chuangyu ointment can inhibit acute inflammation and hyperplasia of granulomatous tissue. Has a good anti-inflammatory effect.