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目的： 观察平脂胶囊对动物血脂和血粘等指标的影响． 方法： 采用高血脂模型，按照酶学、组织化学及直接测压等方法测定血脂、组织中脂质、血液流变、血压等指标． 结果：①０．４ ｇ／ｋｇ， ０．８ ｇ／ｋｇ 平脂胶囊使高血脂小鼠体质量、肝脏系数、肝组织胆固醇（ＴＣ）和血清ＴＣ显著降低（Ｐ＜ ０．０１）； ②对高血压－高血脂大鼠体质量和心脏、主动脉、肝脏系数；血清ＴＣ、甘油三脂（ＴＧ），主动脉、心肌、肝脏组织中ＴＣ， ＴＧ以及全血粘度（高、低切）、血浆粘度和全血比粘度均显著降低（Ｐ＜ ０．０１）；显著升高血清高密度脂蛋白胆固醇（ＨＤＬ－Ｃ） （Ｐ＜０．０１）． 结论： 平脂胶囊对实验性高血脂小鼠和高血压－高血脂大鼠的血脂、血粘、血压和组织中脂质（ＴＣ， ＴＧ）均有明显降低作用．
1. Objective : To observe the effect of Pingzhi capsule on blood fat and blood viscosity of animals. METHODS: Hyperlipidemia model was used to measure lipids, tissue lipids, blood rheology, and blood pressure according to enzymology, histochemistry and direct manometry. RESULTS: The body weight, liver coefficient, liver tissue cholesterol (TC) and serum TC of mice with high cholesterol were significantly reduced by 10.4 g/kg and 0.8 g/kg Pingzhi capsules (P<0.01); Hypertension - Hyperlipidemic rat body weight and heart, aorta, liver coefficient; serum TC, triglyceride (TG), aortic, myocardium, liver tissue TC, TG and whole blood viscosity (high, low cut), The plasma viscosity and specific viscosity of whole blood were significantly decreased (P<0.01); serum high-density lipoprotein cholesterol (HDL-C) was significantly increased (P<0.01). Conclusion: Pingzhi Capsules can significantly reduce blood lipid, blood viscosity, blood pressure and lipids (TC, TG) in experimental hyperlipidemia mice and hypertensive-hyperlipidemic rats.