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在酸性条件下,用铂催化剂氢化尿嘧啶核糖核苷酸和核苷分别获得双氢尿嘧啶核糖核苷酸和核苷.以此制备了它们的衍生物,进一步通过磷酸二酯法,合成了酵母丙氨酸转移核糖核酸D环中含有双氢尿嘧啶核糖核苷酸的片段DpApG,ApGpDpC和ApGpDpCpGpG.同时还合成了含有双氢尿嘧啶核苷的片段ApGpD.其中DpApG还用磷酸三酯法合成过.
Under acidic conditions, dihydrouracil ribonucleotides and nucleosides were obtained by hydrogenation of uracil ribonucleotides and nucleosides with platinum catalysts, respectively, and their derivatives were prepared, and further phosphodiester method was used to synthesize Yeast alanine transfer RNA D ring contains dihydrouracil ribonucleotide fragments DpApG, ApGpDpC and ApGpDpCpGpG also synthesized dihydromyrionine fragment ApGpD which DpApG phosphotriester method Synthesized.