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目的为探讨血清MG7-Ag检测对胃癌诊断价值．方法采用酶免疫法检测了107例消化道各恶性肿瘤患者，32例胃良性疾病患者及34例正常对照者血清MG7－Ag和CEA水平．结果41例胃癌、24例结直肠癌、9例胰腺癌和19例原发性肝癌患者血清MG7－Ag的阳性率分别为46．3％，45．8％，44．4％和42．1％，均显著高于对照组和胃良性疾病组（P＜0．05），其中胃癌稍高，但相互比较，无显著性差别．14例食管癌患者血清MG7-Ag阳性率为28．6％，与胃良性疾病组和对照组比较均无显著性差别；消生道恶性肿瘤患者血清CEA含量与MG7-Ag含量呈大致的平行关系．结论血清MG7－Ag对胃癌的诊断没有很好的特异性，但对消化道恶性肿瘤中的胃癌、结直肠癌、胰腺癌和原发性肝癌的诊断还是一种较灵敏的，相对特异的肿瘤标志物．
Objective To investigate the diagnostic value of serum MG7-Ag detection in gastric cancer. Methods Serum levels of MG7-Ag and CEA were measured in 107 patients with malignant tumors of the digestive tract, 32 patients with benign gastric diseases and 34 normal controls by enzyme immunoassay. Results The positive rates of MG7-Ag in 41 cases of gastric cancer, 24 cases of colorectal cancer, 9 cases of pancreatic cancer and 19 cases of primary liver cancer were 46.3%, 45.8%, 44.4% and 42.1 respectively. %, both significantly higher than the control group and the benign gastric disease group (P <0.05), of which gastric cancer is slightly higher, but compared with each other, no significant difference. The positive rate of serum MG7-Ag in 14 patients with esophageal cancer was 28.6%. There was no significant difference between the patients with benign disease and the control group. Serum CEA levels in patients with malignant tumors were roughly parallel to the MG7-Ag level. relationship. Conclusions Serum MG7-Ag is not very specific for the diagnosis of gastric cancer, but it is also a sensitive and relatively specific tumor for the diagnosis of gastric cancer, colorectal cancer, pancreatic cancer and primary liver cancer in digestive tract malignancies. landmark.