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目的 :研究肝素对尿路导管表面尿盐沉积的影响。方法 :将 183例尿路带有 2 12根导管的病人分成 4组 ,经尿路导管分别灌注肝素稀释液、庆大霉素稀释液、肝素与庆大霉素稀释液交替及 0 .9%氯化钠注射液。对拔出导管表面进行扫描电镜观察及尿盐定性定量分析。结果 :留管wk 2起导管表面尿盐沉积量 0 .9%氯化钠注射液组及庆大霉素组明显高于肝素组和合用组。扫描电镜观察肝素组及合用组比庆大霉素组及 0 .9%氯化钠注射液组导管表面附着层更薄、纤维蛋白网更稀、晶体沉积量更少。结论 :肝素能够阻止尿路导管表面尿盐沉积延缓导管包壳发展
Objective: To study the effect of heparin on urinary saline deposition on urinary catheter surface. Methods: 183 patients with 218 cases of urinary tract catheterization were divided into 4 groups. The heparin solution, gentamycin diluent, heparin and gentamicin dilution were alternately infused through the urinary catheter and 0.9% Sodium chloride injection. The catheter surface was removed by scanning electron microscopy and urine qualitative and quantitative analysis. Results: The amount of urinary saline deposited on the catheter surface from wk 2 was 0. 9% in sodium chloride injection group and gentamicin group was significantly higher than that in heparin group and combination group. Scanning electron microscopy showed that the heparin group and the combination group were thinner than the gentamicin group and the 0.9% sodium chloride injection group. The fibrin network was thinner and the amount of crystal deposition was less. CONCLUSION: Heparin prevents the urinary saline deposits on the catheter surface from delaying the development of the catheter sheath