介入和冠脉搭桥术是主要的冠心病治疗措施 ,而术后再狭窄的发生一直是困扰临床的一个棘手问题。目前采用涂层支架防治再狭窄的效果较好 ,但是价格昂贵且远期效果尚未确定。最近 ,Otterbein等报道大鼠颈总动脉球囊拉伤前预吸入低浓度的一氧化碳 (CO) (2 5 0ppm ,为毒性剂量的 1/ Intervention and coronary artery bypass grafting are the main treatment measures for coronary heart disease. However, the occurrence of postoperative restenosis has always been a thorny problem in clinical practice. The current use of coated stents to prevent restenosis is better, but expensive and long-term effect has not yet been determined. Recently, Otterbein et al reported that pre-inhalation of low concentrations of carbon monoxide (CO) (250 ppm, 1 /