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目的:探讨中药雾化吸入治疗治疗化疗患者口腔溃疡的疗效。方法:2014年9月至2016年3月,商丘梁园牙博士口腔病防治所收治肿瘤化疗后导致口腔溃疡患者100例,随机分为观察组和对照组,每组各50例。对照组患者给予常规外用药物及口腔清洁治疗,给予患者常规0.9%氯化钠注射液漱口,并将口腔溃疡散等药物涂至患者口腔溃疡部位,每日5~6次,7 d为1个疗程,观察组以中药雾化吸入治疗,比较两组患者疼痛缓解以及治疗效果。结果:观察组患者疼痛视觉模拟量表(VAS)评分为(2.03±0.86)分,对照组为(4.39±1.03)分,差异具有统计学意义(P<0.05)。观察组治疗后显效35例,有效13例,无效2例,有效率为96.00%,对照组治疗后显效23例,有效14例,无效13例,有效率为74.00%,差异具有统计学意义(P<0.05)。结论:中药雾化吸入可以明显缓解肿瘤化疗患者的口腔溃疡引起的疼痛,能促进溃疡面的愈合。
Objective: To investigate the curative effect of inhalation of traditional Chinese medicine on oral ulcer in patients undergoing chemotherapy. METHODS: From September 2014 to March 2016, 100 cases of oral ulcer patients who underwent chemotherapy after oral administration of Shangqiu Liangyuan Dental Prevention and Treatment Hospital were randomly divided into observation group and control group with 50 cases in each group. Patients in the control group were given conventional topical drugs and oral cleaning treatment. Patients were given conventional 0.9% sodium chloride injection mouthwash and oral ulcer powder and other drugs were applied to patients with oral ulcers site, 5 to 6 times a day, 7 d 1 A course of treatment, the observation group to inhalation of traditional Chinese medicine treatment, pain relief and treatment of two groups were compared. Results: The pain visual analog scale (VAS) score of the observation group was (2.03 ± 0.86) points and that of the control group was (4.39 ± 1.03) points, the difference was statistically significant (P <0.05). After treatment, the observation group was markedly effective in 35 cases, effective in 13 cases, ineffective in 2 cases, effective rate was 96.00% in the control group after treatment, 23 cases were effective, 14 cases were effective, ineffective in 13 cases, the effective rate was 74.00%, the difference was statistically significant P <0.05). Conclusion: The inhalation of traditional Chinese medicine can obviously relieve the pain caused by oral ulcer in patients with tumor chemotherapy, and promote the healing of ulcer surface.