肝病末期常并发肝肾综合征和水、盐代谢紊乱等多种肾功能异常。肝脏疾病也同样可出现肾小球形态上和功能上的变化。在病毒性肝炎、某些传染病、脉管炎、红斑性狼疮以及冷沉球蛋白血症中,肝病和肾小球病可以并存。在与肝硬变相关的肾小球病变中,多数能看到肾小球膜内有IgA沉积和少量其它免疫球蛋白以及C_3的沉积。晚期肝病病人中出现这些组织学改变者称之为肝硬变性肾小球肾炎(下称肝硬变性GN)。肝硬变性GN应否看作是特殊的疾病实体尚有争议,但1981年出版的教科书“肾脏”和近年出版的教科书,“肝病中的肝脏”已接受此概念。Beryer等 End-stage liver disease often complicated by hepatorenal syndrome and water, salt metabolism disorders and other renal dysfunction. Liver disease can also occur glomerular morphological and functional changes. In viral hepatitis, certain infectious diseases, vasculitis, lupus erythematosus, and cryoglobulinemia, liver disease and glomerulopathy can coexist. In cirrhosis-related glomerular lesions, the majority can see IgA deposition within the mesangium and the deposition of small amounts of other immunoglobulins and C_3. The occurrence of these histological changes in patients with advanced liver disease called cirrhosis glomerulonephritis (hereinafter referred to as cirrhosis GN). Whether or not cirrhosis GN should be considered a particular disease entity is controversial, but the textbook Kidney in 1981 and the textbook published in recent years Liver in Liver Disease have accepted this concept. Beryer et al