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目的:观察ILD患者LEP的改变及糖皮质类固醇对LEP的影响。材料和方法:12例临床或病理诊断为ILD患者。10名健康人作对照组。采用喷气雾化器吸入99mTcDTPA气溶胶测定LEP。结果:ILD患者左肺、左肺上野、左肺中野、右肺、右肺中野的LEP显著升高。左肺上野的T1/2与DLCO、DLCO%及PaO2呈正相关。结论:(1)临床观察ILD患者的LEP,尤应注意肺中野;(2)LEP与DLCO及PaO2存在较好的一致性;(3)类固醇并不能改善ILD不可逆病变的LEP。
Objective: To observe the changes of LEP in patients with ILD and the effect of glucocorticoid on LEP. Materials and Methods: Twelve patients with ILD were diagnosed clinically or pathologically. 10 healthy people as control group. Using jet nebulizer inhalation 99mTc DTPA aerosol determination of LEP. Results: LEP in left lung, left upper field, left middle field, right lung and right lung of ILD patients were significantly increased. T1 / 2 in the left lung Ueno was positively correlated with Dlco, Dlco% and PaO2. Conclusions: (1) Clinical observation of LEP in patients with ILD should be paid more attention to the middle of the lung; (2) There is a good agreement between LEP and DLCO and PaO2; (3) Steroid does not improve LEP in irreversible lesions of ILD.