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作者等1984年以来在香港先后发现管圆线虫引起的嗜酸粒细胞性脑膜炎4例。本文比较了病人的临床症状和实验室资料。用ELISA试验检测患者血清及脑脊液(CSF)中抗广州管圆线虫、抗犬弓蛔虫和抗刚棘颚口线虫的IgG抗体。用间接荧光抗体试验(IFAT)检测死者的脑组织切片,分别以正常兔血清及感染广州管圆线虫25天的鼠脑作对照。男、女性各2例,年龄分别为2、30、10和60岁。依次编为1~4号。将GSF作革兰氏染色和培养均未查见微生物。患者均有低
In 1984, the author discovered four cases of eosinophilic meningitis caused by C. elegans in Hong Kong. This article compares the patient’s clinical symptoms and laboratory data. Serum and cerebrospinal fluid (CSF) were tested for IgG antibodies to C. elegans, C. caninii and S. japonicus using ELISA assays. Indirect fluorescent antibody test (IFAT) was used to detect the brain tissue of the deceased. The normal rabbits’ sera and 25-day-old mouse brain infected with A. cantonensis were used as controls. 2 males and 2 females, aged 2, 30, 10 and 60 years old respectively. In turn numbered 1 to 4. The GSF was Gram stain and culture were not found in the micro-organisms. Patients are low