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目的 探讨绝经后妇女雌激素水平与血脂及血糖变化的规律。方法 70例绝经期妇女分为高血脂及糖耐量异常组 (A组 )和无高血脂及糖耐量异常组 (B组 ) ,35例正常行经妇女为对照组 (C组 ) ;均进行血脂、血糖及性激素水平测定 ,并进行相关性分析。结果 A组雌激素水平显著低于B组和C组 ,而卵泡刺激素、黄体生成素显著高于B组和C组。总胆固醇、甘油三酯、低密度脂蛋白胆固醇及血糖与血清雌二醇呈直线负相关。结论 绝经后妇女血脂及糖耐量异常与血清雌二醇水平降低密切相关。
Objective To investigate the changes of estrogen levels, blood lipids and blood glucose in postmenopausal women. Methods Seventy menopausal women were divided into hyperlipidemia and impaired glucose tolerance group (group A), hyperlipidemia and impaired glucose tolerance group (group B), and 35 normal women as control group (group C) Blood glucose and sex hormone levels were measured, and correlation analysis. Results The estrogen level of group A was significantly lower than that of group B and C, while the levels of follicle stimulating hormone and luteinizing hormone were significantly higher than those of group B and C. Total cholesterol, triglycerides, low density lipoprotein cholesterol and blood glucose and serum estradiol showed a negative linear correlation. Conclusion The postmenopausal women with abnormal blood lipid and glucose tolerance and serum estradiol levels are closely related.