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薄荷油和桉油是常用的外用治疗头痛药物。薄荷油局部用药时通过改变冷受体钙通道的立体结构而对皮肤产生长时间的凉爽效应,在动物实验中,薄荷油可以非竞争性地抑制三叉神经—血管系统中重要介质5-羟色胺和 P 物质诱导的平滑肌收缩;能阻断钙通道而松弛颅骨膜肌肉;局部外用时可以增加
Peppermint oil and oyster sauce are commonly used topical headache medications. Peppermint oil has a long-term cooling effect on the skin by altering the three-dimensional structure of the cold receptor calcium channel when administered topically. In animal experiments, peppermint oil can non-competitively inhibit the important media serotonin in the trigemino-vascular system and P substance induces smooth muscle contraction; can block calcium channels and relax the cranial periosteum muscles; can increase when topical