论文部分内容阅读
目的探讨妊娠期急性脂肪肝的临床特点,以便早期诊断和及时治疗,降低母婴病死率。方法对驻马店市中心医院5年来收治的26例妊娠期急性脂肪肝患者的临床资料进行回顾性分析。结果 26例孕产妇中23例存活,3例死亡;3 l例胎儿(其中5例为双胎)中,死胎3例,新生儿死亡3例;产妇病死率为11.5%,围生儿死亡率为19.4%。结论妊娠期急性脂肪肝发病突然,病情重,孕产妇、新生儿病死率高,早期诊断、及早终止妊娠、积极支持治疗、多学科综合治疗可有效降低母婴病死率。
Objective To investigate the clinical features of acute fatty liver in pregnancy so that early diagnosis and timely treatment can reduce the maternal and infant mortality. Methods The clinical data of 26 patients with acute fatty liver during pregnancy admitted to Zhumadian Central Hospital in 5 years were analyzed retrospectively. Results Twenty-three of 26 pregnant women survived and 3 died. Among 3 l fetuses (5 were twins), 3 were stillbirths and 3 were neonatal deaths. The maternal mortality rate was 11.5% and the perinatal mortality rate 19.4%. Conclusions The incidence of acute fatty liver during pregnancy is suddenly and severely exacerbated. Maternal and neonatal mortality is high. Early diagnosis and early termination of pregnancy support active treatment. Comprehensive multidisciplinary treatment can effectively reduce maternal and infant mortality.