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四十余种中药煎剂,相当于生药10—20克/公斤的剂量,灌胃给予盐水负荷的大白鼠以进行利尿试验。其中益母草、淡竹叶、虫筍、瞿麦、酸浆、桑白皮、半边莲、黄耆、白术和马鞭草都有较明显的利尿和/或利钠作用,而前五药的作用可能主要由于生药中所含钾盐引起;其它如木通、防已、茅根、地肤子、黄芩、萆藓、石苇、广地龙、郁李仁、薏苡仁、商陆、甘遂、千金子、吴茱萸、大腹皮,红大戟、通草、灯心草,萱草、麻黄、路路通,茯苓、桂枝、车前子、香薷、石斛、旋复花、浮萍、葶藶子、秦艽、泽泻、牵牛子等32种单药及五苓散、五皮饮、黄耆防已汤3复方对大白鼠尿量和尿钠排出量皆不见有何明显影响。
More than 40 kinds of Chinese medicine decoction, equivalent to crude drug 10-20 g / kg dose, gavage saline-loaded rats for diuretic tests. Among them, motherwort, light bamboo leaves, insect bamboo shoots, buckwheat, Physalis, Morus alba, Lobelia jasminoides, Astragalus, Atractylodes macrocephala, and Verbena officinalis all have obvious diuretic and/or natriuretic effects. The effect of the first five drugs may be mainly due to Potassium salt contained in crude drug; Others such as Mutong, Fangchuang, Chaigen, Kochia scoparia, Astragalus, Poria, Dendrobium, Guangdi Long, Yu Liren, Coix Seed, Shanglu, Ganzi, Qianjin, Wujing, Large belly, red Daxue, Tongcao, rushes, valerian, ephedra, road pass, wolfberry, cassia twig, plantago, citron, sargentia, spinosa, duckweed, medlar, Gentiana, Alisma, lead Niu Zi and other 32 kinds of single drug and Wuhao San, Wupi Yin, Huang Fu Fang De Tang 3 compound on urine output and urinary sodium excretion in rats did not have any significant effect.