IL-1、IL-2可能参与机体对感染刺激的起初反应和免疫球蛋白产生;本文研究了这些细胞因子是否参与囊性纤维变性(CF)时增强的全身炎症反应,并观察它们之间的相互关系及免疫球蛋白与气道阻塞之间的关系。 患者和方法:37例10、5(5～19)岁临床上稳定的CF患者,对其痰进行常规细菌学检测,以呼吸量测定法测FEV_1及FVC,并采血检测IgG、IgM、IgE浓度, IL-1, IL-2 may be involved in the initial response of the body to the stimulation of infection and immunoglobulin production. In this paper, we investigated whether these cytokines participate in the enhanced systemic inflammatory response in cystic fibrosis (CF) Relationship and relationship between immunoglobulin and airway obstruction. PATIENTS AND METHODS: Thirty-seven patients with clinically stable CF of 10,5 (5-19 years) were routinely bacteriologically examined for sputum, FEV 1 and FVC were measured by spirometry, and serum concentrations of IgG, IgM and IgE ,