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骨质疏松症(osteoporosis,OP)是一种常见的代谢性骨病,其特征为骨量减少和骨组织微结构破坏,骨骼脆性增加和骨折风险增大。糖尿病是一种糖、脂代谢异常综合征,长期慢性高血糖致骨形成和骨微环境发生整体性的改变,易合并骨代谢异常及骨质疏松。根据文献报道糖尿病性骨质疏松发病率为38.3%～71%,其发病机制可能与胰岛素的缺乏或作用不足引起体内物质代谢障碍,大量蛋白质和氨基酸被消耗,骨组织内糖蛋白和Ⅰ
Osteoporosis (OP) is a common metabolic bone disease characterized by reduced bone mass and destruction of the microstructure of bone tissue, increased bone fragility and increased risk of fracture. Diabetes mellitus is a syndrome of sugar and lipid metabolism, long-term chronic hyperglycemia caused by bone formation and bone microenvironment changes in the overall, easy to merge with bone metabolism and osteoporosis. According to the literature reported that the incidence of diabetic osteoporosis was 38.3% to 71%, the pathogenesis may be related to lack of or lack of insulin cause physical metabolism disorders, a large number of proteins and amino acids are consumed, bone tissue glycoprotein and Ⅰ