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用放免法测定了48例肝硬化患者血清类洋地黄物质水平。结果全部患者明显高于对照组。该物质在代偿期已有升高;失代偿期升高更为显著,其程度与腹水量相关。中~大量腹水患者的血清类洋地黄物质水平与血清白蛋白及血钠浓度呈显著负相关。提示血清类洋地黄物质水平的测定可作为估计肝硬化严重程度及预后的一个指标。
48 cases of patients with cirrhosis serum digitalis content was determined by radioimmunoassay. Results All patients were significantly higher than the control group. The substance has increased in the compensatory period; decompensation increased more significantly, the degree associated with ascites. In mid-large ascites serum creatinine levels and serum albumin and serum sodium concentration was significantly negatively correlated. It is suggested that the determination of serum digitalis level can be used as an index to evaluate the severity and prognosis of cirrhosis.