论文部分内容阅读
目的:观察慢性心力衰竭患者血B型钠尿肽前体N末端(NT-proBNP)的变化。方法:应用电化学发光法检测89例收缩性心力衰竭(收缩性心力衰竭组)和17例单纯舒张功能不全性心力衰竭患者(DHF组)以及22例心功能正常的对照组的血NT-proBNP水平。结果:收缩性心力衰竭组不同心功能级别患者的NT-proB-NP均显著高于对照组,且自Ⅰ~Ⅳ级心功能的NT-proBNP逐级升高,分别为(388·9±304·7)、(772·7±648·4)、(1946·4±1914·4)和(3743·4±2592·5)ng/L,DHF组为(578·1±848·3)ng/L,对照组为(69·5±51·2)ng/L。结论:血NT-proBNP的检测有助于对慢性心力衰竭的诊断。
Objective: To observe the changes of N-terminal pro-brain natriuretic peptide (BNP) precursor levels in patients with chronic heart failure. Methods: The blood levels of NT-proBNP in 89 patients with contracted heart failure (systolic heart failure group) and 17 patients with simple diastolic heart failure (DHF group) and 22 patients with normal cardiac function were measured by electrochemiluminescence. Level. Results: NT-proBNP in patients with different levels of cardiac function in systolic heart failure group were significantly higher than those in control group, and NT-proBNP levels from Ⅰ to Ⅳ were increased gradually (388.9 ± 304 (772.7 ± 648.4), (1946.4 ± 1914.4) and (3743.4 ± 2592.5) ng / L, respectively. The DHF group was (578.1 ± 848.3) ng / / L in the control group and (69.5 ± 51.2) ng / L in the control group. Conclusion: The detection of blood NT-proBNP contributes to the diagnosis of chronic heart failure.