对１８例慢性酒精中毒性Ｗｅｒｎｉｃｋｅ脑病进行了分析。发现其起病形式多呈急性；临床表现以精神异常、眼运动障碍及共济失调三联征为主，但典型的三联征并不是每例患者所必备；其病因主要是维生素Ｂ１缺乏；血中丙酮酸测定有助于诊断；及时确诊，并早期治疗是治疗本病的关键。 Eighteen patients with chronic alcoholic Wernicke encephalopathy were analyzed. Found that most of its acute form of onset; clinical manifestations of mental disorders, eye movement disorders and ataxia based triplet, but the typical triad is not essential for every patient; its causes are mainly vitamin B1 deficiency; blood Determination of pyruvate helps to diagnose; timely diagnosis, and early treatment is the key to the treatment of this disease.