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目的探讨布地奈德雾化联合盐酸丙卡特罗治疗小儿肺炎的临床效果。方法收集小儿肺炎患者90例,随机分为对照组和观察组,各45例。对照组在常规抗感染(抗生素选择依据药敏或患儿病史)、抗病毒、退热、解痉平喘等对症治疗的基础上,给予布地奈德雾化吸入治疗,将布地奈德2 ml加入0.9%氯化钠注射液2 ml,氧动力雾化吸入,时间10~15 min,每天1~3次,持续1周。观察组在对照组治疗的基础上给予盐酸丙卡特罗口服治疗,每天1次,每次25 g,持续1周。比较两组治疗有效率、症状体征消失时间及不良反应发生率。结果对照组治疗总效率为88.89%,观察组为95.56%,两组差异有统计学意义(<0.05)。观察组症状体征消失时间均明显短于对照组(均<0.05)。结论布地奈德雾化联合盐酸丙卡特罗治疗小儿肺炎,能够迅速缓解患儿症状,提高治疗有效率,不良反应小,具有临床推广的重要意义。
Objective To investigate the clinical efficacy of budesonide atomization combined with procaterol hydrochloride in children with pneumonia. Methods Ninety children with pneumonia were collected and randomly divided into control group and observation group, with 45 cases in each group. The control group received budesonide inhalation therapy on the basis of conventional anti-infective (antibiotic selection based on drug susceptibility or history of children), symptomatic treatment such as antivirus, antipyretic, antispasmodic and asthma treatment. The budesonide 2 ml was added to 0.9 % Sodium chloride injection 2 ml, aerodynamic inhalation, time 10 ~ 15 min, 1 to 3 times a day for 1 week. The observation group was treated with Procaterol Hydrochloride orally on the basis of the control group, once a day for 25 g each for 1 week. Compare the two groups of treatment efficiency, the disappearance of symptoms and signs and the incidence of adverse reactions. Results The total effective rate of the control group was 88.89%, the observation group was 95.56%, the difference between the two groups was statistically significant (<0.05). Observation group symptoms and signs disappeared significantly shorter than the control group (all <0.05). Conclusion Budesonide atomization combined with procaterol hydrochloride in children with pneumonia can rapidly relieve the symptoms of children and improve the treatment efficiency, with small adverse reactions, with clinical significance.