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目的:研究分析彩超和谷氨酰转肽酶(GGT)联合检测对酒精依赖患者酒精性脂肪肝诊断的临床意义。方法:对2013年5月-2014年4月于我院住院并诊断为酒精依赖的患者39例(研究组)行肝脏彩超及GGT检测,另选取同期来源于本院职工、进修医护人员40例为对照组,对其结果进行分析。结果:研究组血清GGT为(189.95±226.52)U/L,显著高于对照组的(26.85±18.94)U/L,差异有统计学意义(t=4.54,P<0.001);研究组中彩超诊断为脂肪肝者的GGT水平与非脂肪肝者有明显差异(P<0.05),且高于对照组中的脂肪肝者,差异有统计学意义(P<0.05)。结论:对于酒精依赖患者,血清GGT是敏感性较高的检测指标,GGT的检测有利于酒精性疾病的早期发现。彩超与GGT联合检测能提高临床对酒精性脂肪肝的检出率。
Objective: To study the clinical significance of the combination of ultrasonography and glutamyl transpeptidase (GGT) in the diagnosis of alcoholic fatty liver in alcohol dependent patients. Methods: Thirty-nine patients (study group) who were hospitalized and diagnosed as alcohol dependence in our hospital from May 2013 to April 2014 underwent liver color Doppler and GGT tests. Forty patients For the control group, the results were analyzed. Results: The serum GGT in the study group was (189.95 ± 226.52) U / L, which was significantly higher than that in the control group (26.85 ± 18.94 U / L, t = 4.54, P <0.001) The GGT level in patients with fatty liver was significantly higher than that in non-fatty liver patients (P <0.05), and the difference was statistically significant (P <0.05). Conclusions: Serum GGT is a sensitive indicator of alcohol dependence and detection of GGT is beneficial for the early detection of alcoholic disease. Color Doppler ultrasound and GGT joint detection can improve the clinical detection rate of alcoholic fatty liver.