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目的:探讨奥美拉唑联合法莫替丁治疗反流性食管炎临床效果。方法:选取100例反流性食管炎患者,随机分为对照组和观察组,每组各50例,对照组给予奥美拉唑治疗,观察组在对照组基础上加用法莫替丁治疗。对两组患者临床疗效进行比较分析。结果:观察组患者治疗总有效率为94%,明显优于对照组的74%;观察组内镜下病变改善总有效率为96%,明显优于对照组的78%,差异均具有统计学意义(P<0.05)。结论:奥美拉唑联合法莫替丁治疗反流性食管炎,可显著改善临床症状,保障预后,对改善患者生存质量意义重大,值得临床推广应用。
Objective: To investigate the clinical effects of omeprazole and famotidine in the treatment of reflux esophagitis. Methods: 100 patients with reflux esophagitis were randomly divided into control group and observation group, 50 cases in each group. The control group was treated with omeprazole. The observation group was treated with famotidine on the basis of the control group. The clinical efficacy of the two groups were compared. Results: The total effective rate was 94% in the observation group, which was significantly better than 74% in the control group. The total effective rate in the observation group was 96%, which was significantly better than 78% in the control group, the difference was statistically significant Significance (P <0.05). Conclusion: Omeprazole combined with famotidine in the treatment of reflux esophagitis can significantly improve clinical symptoms and protect the prognosis, which is of great significance to improve the quality of life of patients and is worthy of clinical application.