论文部分内容阅读
用放免法测定２７例正常人和２６例原发肾小球肾炎血浆内皮素（ＰＥＴ），并按水肿不同程度、病理类型及２４小时尿蛋白的定量多少分别与ＰＥＴ进行分析。结果显示ＰＥＴ与不同病理类型、２４小时尿蛋白定量多少均无相关（Ｐ＞０．０５）。肾小球肾炎高度水肿组与轻度水肿组、无水肿组ＰＥＴ比较差异显著（Ｐ＜０．０５）。肾炎组与正常人组的ＰＥＴ比较有明显升高（Ｐ＜０．００１）。提示ＰＥＴ可能参与肾炎的免疫发病机理和水钠潴留的病理过程。
27 cases of normal subjects and 26 cases of primary glomerulonephritis were treated with radioimmunoassay. The levels of plasma endothelin (PET) were analyzed by PET, according to the degree of edema, the pathological type, and the quantitation of 24-hour urinary protein. The results showed that there was no correlation between the quantity of PET in different pathological types and 24-hour urinary protein (P> 0.05). There was significant difference in PET between glomerulonephritis with high degree of edema, mild edema and no edema (P <0.05). Nephritis group and normal PET group was significantly higher (P <0.001). Tip PET may be involved in the immune pathogenesis of nephritis and Shuinazhuliu pathological process.