人类天然生长抑素为十四肽，有抑制垂体前叶分泌生长激素（GH）的功能，但其半衰期非常短（3～5分钟），不适于临床应用。国外于八十年代中期开发出半衰期长（约2小时）、结构类似的环状八肽生长抑素Sandostatin，并用于垂体GH瘤的试验性临床治疗。我们于1992年用此药完成3例病 Human natural somatostatin is tetradecanoyl peptide, which inhibits the secretion of growth hormone (GH) in the anterior pituitary. However, its half-life is very short (3 to 5 minutes) and is not suitable for clinical application. In the mid-1980s, Sandostatin, a long-lived half-life (about 2 hours) and structurally similar cyclic octapeptide somatostatin, was developed and used for experimental clinical treatment of pituitary GH tumors. We used this medicine to complete 3 cases of illness in 1992