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多数新生儿单纯疱疹病毒(HSV)感染病例,因在其病程中出现典型的皮肤、眼或口咽病损,而作出诊断。但播散性HSV感染与HSV脑炎的新生儿也可不出现皮肤粘膜病损,这也许是本病易于漏诊的原因。据作者经验,患播散性HSV感染与HSV脑炎新生儿中,仅30%曾有疱疹性皮肤、眼或口腔病损。因目前已有针对HSV的有效抗病毒药物,故早期认识新生儿HSV感染的临床特征,使之早期确诊至为重要。又因新生儿HSV感染常来自母亲生殖道HSV感染,故正确诊断本病对其母
Most neonatal herpes simplex virus (HSV) infections are diagnosed because of typical skin, eye, or oropharyngeal lesions during their course of disease. However, disseminated HSV infection and HSV encephalitis in newborns may not appear mucocutaneous lesions, which may be the reason for the misdiagnosis of the disease. According to the author’s experience, only about 30% of newborns with disseminated HSV infection and HSV encephalitis have had herpes dermatosis, ocular or oral lesions. Because of the current effective antiviral drugs against HSV, so early recognition of neonatal HSV infection clinical features, so that the early diagnosis is of great importance. Because of neonatal HSV infection often comes from the mother’s reproductive tract HSV infection, so the correct diagnosis of the disease on the mother