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慢性呼吸道感染常常伴有慢性支气管扩张,多达四分之一的病例由铜绿假单胞菌引起,并可导致病情进展更快,病死率升高。Haworth等在支气管扩张伴铜绿假单胞菌感染(非囊胞性纤维化症)成年患者中,进行雾化吸入多黏菌素的疗效及耐受性研究。受试者为英国、俄罗斯及乌克兰等国的35个医疗中心、12个月内≥2次呼吸道标本中分离出铜绿假单胞菌的支气管扩张患者且纳入研究后21 d内出现感染
Chronic respiratory infections are often accompanied by chronic bronchiectasis, and as many as a quarter of cases are caused by Pseudomonas aeruginosa and can lead to faster disease progression and increased mortality. Haworth et al in the bronchiectasis with Pseudomonas aeruginosa infection (non-cystic fibrosis) adult patients, the effect of atomized inhaled polymyxin and tolerance study. Subjects were 35 medical centers in the United Kingdom, Russia and Ukraine, bronchodilators with Pseudomonas aeruginosa were isolated from ≥2 respiratory samples in 12 months and were infected within 21 days after enrollment