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介绍了利用同位素交换反应制备肝癌治疗剂￣（１２５）Ｉ－碘化油。用乙醇为反应介质，在１００℃下标记反应２０ｍｉｎ，回收率达９２％，经纸色层法及高压液相色谱（ＨＰＬＣ）测定，￣（１２５）Ｉ－碘化油的放化纯度＞９８％；经红外光谱分析，放射性碘标记并不改变碘化油的分子结构，并且标记物稳定性好，室温下放置一个月，标记物放化纯度无明显降低。
Introduced the use of isotope exchange reaction preparation of liver cancer therapeutic agent ~ (125) I-iodized oil. Using ethanol as the reaction medium, the reaction was marked at 100 ℃ for 20 min, the recovery rate was 92%. The radiochemical purity of ~ (125) I-iodized oil was> 98 as determined by paper chromatography and high pressure liquid chromatography (HPLC) %; By infrared spectroscopy, radioactive iodine labeling does not change the molecular structure of iodized oil, and the stability of the label, placed at room temperature for one month, the radiochemical purity of the label was not significantly reduced.