同型半胱氨酸(Homocysteine,Hcy)又称高半胱氨酸,是一种体内不能合成的含硫四碳氨基酸,其既是蛋氨酸循环的正常代谢产物,也是能量代谢和许多需甲基化反应的重要中间产物。近年来,许多学者和研究机构对高同型半胱氨酸如何诱导神经细胞凋亡的机制进行了研究和探讨。但是目前有关Hcy如何损伤神经系统,以及引发神经退行性病变的具体机制尚不清楚。 Homocysteine ​​(Hcy), also known as homocysteine, is a sulfur-free four-carbon amino acid that can not be synthesized in vivo. It is not only the normal metabolite of methionine cycle, but also energy metabolism and many methylation reactions The important intermediate product. In recent years, many scholars and research institutions on the homocysteine ​​how to induce apoptosis in neurons mechanism were studied and discussed. However, the exact mechanism by which Hcy damages the nervous system and causes neurodegenerative diseases remains unclear.