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目的为了改善癌症患者化疗期间生活质量。方法1991年12月至1994年12月期间，对30例癌症患者进行了甲孕酮（MPA）治疗的临床观察，设对照组30例。结果口服MPA的癌症患者普遍反映精神、食欲好转，体重有所增加，生活质量综合指数NPS评分较治疗前明显提高（80％，对照组为36．7％，P＜0．01），伴有痛疼的患者（计18例）的癌痛改善率治疗组为83．3％，显著高于对照组的41％。结论甲孕酮（MPA）可以广泛用于各种肿瘤的化疗期间，来改善患者生活质量。
Objective To improve the quality of life of cancer patients during chemotherapy. Methods From December 1991 to December 1994, 30 cases of cancer patients were treated with medroxyprogesterone (MPA). There were 30 cases in the control group. Results: Patients with oral MPA generally reported improvement in spirit, appetite and weight, and the quality of life NPS score was significantly higher than before treatment (80%, 36.7% in the control group, P<0.01). The improvement rate of cancer pain in patients with pain (18 cases) was 83.3% in the treatment group, which was significantly higher than the 41% in the control group. Conclusion Megestrol acetate (MPA) can be widely used during the chemotherapy of various tumors to improve the quality of life of patients.