原发性糖尿病是一种遗传性疾病。糖尿病的遗传因素虽已肯定,但遗传基因的特征及传递方式等问题尚不十分清楚。1983年12月第15届国际遗传学会在印度新德里召开前后,国外有关糖尿病的遗传学说,遗传方式和基因的作用机理,HLA抗原与糖尿病遗传的关系,糖尿病基因型发病的诱发因素,特异质基因的遗传性疾病伴发糖尿病等临床研究,国外有不少报道。笔者复习国外近期研究资料,结合临床工作中的体会,仅就糖尿病的遗传病因、机理,及糖尿病与遗传相关的问题略作概述。 Primary diabetes is a hereditary disease. Although the genetic factors of diabetes have been affirmed, but the characteristics of the genetic and delivery methods and other issues is not yet clear. 1983 December 15th International Genetics Society held in New Delhi, India before and after the foreign genetic theory of diabetes, the mode of genetics and gene mechanism of action, the relationship between HLA antigen and diabetes inheritance, predisposing factors for the onset of diabetes genotype, Gene genetic disease associated with diabetes and other clinical studies, many foreign reports. The author review recent foreign research data, combined with the clinical experience, only the genetic causes of diabetes mellitus, mechanism, and diabetes and genetic issues briefly outlined.